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Alzheimer's Research Yields Potential Drug Target
Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer"s disease. Scientists say the discovery may lead to new drugs for the disease.
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New Image Survey Reveals 'Perception Is Reality' When It Comes To Teenagers With Acne
In today"s image-obsessed society where millions of photos are uploaded daily through digital networks such as Facebook and Flickr, how much of an impact can a common skin condition like acne have on the life of teens? Based on first impressions, teens with acne are perceived to have different personality and social traits than if they had clear skin, according to results of a new online perception survey sponsored by the American Acne & Rosacea Society (AARS), and co-authored by Dr. Eva Ritvo, psychiatrist and co-author of The Beauty Prescription.(1) The survey asked thousands of teens and adults to offer their impressions of a group of teens based solely on photos of their faces - with clear skin or digitally enhanced to simulate acne. The results, which are being released to mark the first-ever National Acne Awareness Month, also expose the significant lengths that teens with acne would go to if it meant they could get rid of their acne forever.(1a)
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Cost-Effective Measures Could Stop Child Pneumonia Deaths
Implementing measures to improve nutrition, indoor air pollution, immunization coverage and the management of pneumonia cases could be cost-effective and significantly reduce child mortality from pneumonia, according to a study led by the Johns Hopkins Bloomberg School of Public Health. Researchers found that these strategies combined could reduce total child mortality by 17 percent and could reduce pneumonia deaths by more than 90 percent. Pneumonia is a leading cause of death of infants in many developing countries, resulting in 2.2 million deaths each year. The study is published in the June 2009 issue of the Bulletin of the World Health Organization.
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Whole Genome Sequencing Of Multiple Myeloma Samples To Be Performed By MMRF And The Broad Institute

The Multiple Myeloma Research Foundation (MMRF) has announced a collaboration with the Broad Institute of MIT and Harvard to systematically uncover the molecular changes underlying multiple myeloma by whole genome sequencing of individual patient tumors. The MMRF will provide both patient samples for analysis as well as funding for the project. All data from this collaboration will be put in the public domain. "We are delighted to work with the MMRF, which has been a visionary organization in accelerating cancer research for the sake of patients and their families," said Eric S. Lander, PhD, Director of the Broad Institute. "Through our work together on this critical pilot project in whole cancer genome sequencing, we hope not only to advance clinical progress for multiple myeloma, but to build knowledge and technical capabilities that can be applied to many other human cancers." "Three years ago, the MMRF launched a partnership with the Broad Institute and the Translational Genomics Research Institute - the Multiple Myeloma Genomics Initiative - a comprehensive genome mapping program to identity new targets and eventually new therapies for this incurable disease," said Kathy Giusti, Founder and CEO of the MMRF, and a multiple myeloma patient. "As part of that larger effort, we are confident that this groundbreaking research will accelerate the development of next-generation treatments to extend the lives of multiple myeloma patients. Additionally, we believe that this work will not only ultimately pave the way to a cure for patients with multiple myeloma, but will benefit patients with other types of cancer." The creation of comprehensive catalogs of all commonly occurring cancer mutations is a current approach of several national and international consortia, including The Cancer Genome Atlas (TCGA) led by the US National Institutes of Health and the International Cancer Genome Consortium (ICGC), to understand major tumor types such as leukemia, lung cancer, glioblastoma and others. To date, only a handful of whole cancer genomes have been sequenced and only one has been published. "The few cancer genomes sequenced to date have been informative, but we need many more to transform cancer research and ultimately cancer therapy," said Stacey Gabriel, PhD, Co-Director of the Broad Institute"s Genome Sequencing and Analysis Program. "This exciting collaboration with the MMRF will advance these goals by contributing public domain data." Nicole Davis Broad Institute of MIT and Harvard


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