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Ablynx Announces A Novel Preclinical Development Candidate Targeting IL6R
Ablynx [Euronext Brussels: ABLX], a pioneer in the discovery and development of Nanobodies®, a novel class of antibody-derived therapeutic proteins, announced that it has advanced ALX-0061, a new Nanobody®-based therapeutic programme, into preclinical development for the treatment of autoimmune and inflammatory diseases.

Penn Medicine Honored For Its Historic Role In The History Of Microbiology
The University of Pennsylvania was honored by The American Society for Microbiology last Friday with a plaque dedication ceremony celebrating the designation of its third Milestones in Microbiology site. Formerly known as the Laboratory of Hygiene, the current Vagelos Laboratories resides on the University of Pennsylvania campus. Honorary speakers included Arthur H. Rubenstein, MBBCh, Dean, University of Pennsylvania School of Medicine; Alison O"Brien, PhD, President, American Society for Microbiology; and William B. Whitman, PhD, Trustee and Director of the Editorial Offices, Bergey"s Manual Trust.
News of the day
Researchers Profile Gene Activity In Acutely Ill Idiopathic Pulmonary Fibrosis Patients
New research may help doctors pinpoint when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill. The findings may also point the way to interventions that could sustain the lives of IPF patients until life-saving transplants could be performed.
Mental Health

Type 2 Diabetes: An Epidemic Among America's Youth

With the number of children suffering from type 2 diabetes growing at an alarming rate, physicians gathered Saturday to discuss strategies for prevention and treatment of the disease among children and adolescents at the American Association of Clinical Endocrinologists (AACE) 18th Annual Meeting & Clinical Congress. "Type 2 diabetes is extremely complex," said A. Jay Cohen, MD, FACE, session moderator and pediatric endocrinologist. "The rapid rise in obesity, physical inactivity and the consumption of excessive calories seems to have led to the epidemic of children with type 2 diabetes." The National Institutes of Health (NIH) is conducting two clinical trials in order to identify the children at risk for type 2 diabetes and to demonstrate the effectiveness of lifestyle intervention among youth. The first trial, HEALTHY, is following a group of about 6,400 children through middle school, from sixth to eighth grade, to determine if modifications in exercise programs and nutrition in the school environment can reduce the risk of children having the disease. Researchers are tracking the youth"s body mass indices (BMIs), fasting glucose levels and fasting insulin levels to show the health benefits of lifestyle adjustments. TODAY, the second trial, is exploring the best treatment options for children with type 2 diabetes. "It is imperative to expose the social, behavioral and environmental factors which have led to this epidemic," said Francine R. Kaufman, MD, pediatric endocrinologist and Study Chair of both trials. Children with type 2 diabetes may be afflicted with other conditions associated with type 2 diabetes, including obesity, hypertension, hyperlipidemia (elevated cholesterol), and potential risks of infertility such as Polycystic Ovarian Syndrome. These youth also have an increased risk of developing long-term complications, including heart disease, stroke, kidney disease, and nerve damage. With results from the HEALTHY trial anticipated to be released this fall, Dr. Kaufman remains optimistic: "The research from these trials will allow us to identify and implement the necessary lifestyle changes that will ultimately foster the health and well-being of not only those at risk but generations of children to come." About AACE AACE is a professional medical organization with more than 6,200 members in the United States and 92 other countries. Founded in 1991, AACE is dedicated to the optimal care of patients with endocrine problems. AACE initiatives inform the public about endocrine disorders. AACE also conducts continuing education programs for clinical endocrinologists, physicians whose advanced, specialized training enables them to be experts in the care of endocrine diseases such as diabetes, thyroid disorders, growth hormone deficiency, osteoporosis, cholesterol disorders, hypertension and obesity. American Association of Clinical Endocrinologists


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