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How To Confirm The Causes Of Iron Deficiency Anemia In Young Women
Iron-deficiency anaemia (IDA) is commonly seen in women aged under 50 years. The diagnostic workflow in young women affected by IDA is not clearly established. The British Society of Gastroenterology recommends gastroscopy only in IDA women younger than 45 years presenting with gastrointestinal (GI) symptoms. However, symptoms are often mild and aspecific in IDA women and the gastroscopy is an invasive procedure associated with a high number of refusals. In a previous work on IDA premenopausal women, gastroscopy was performed in all patients, later deemed unnecessary in almost 30% of the studied women because these were affected only by menorrhagia.

Primary Health Care Trusts Face Court Action Over Alcohol Treatment Failings, UK
Primary Health Care Trusts (PCTs) the length of England could soon find themselves in the High Court over the pitiful lack of appropriate treatment being offered to those with severe alcohol problems following an audit carried out by pressure group UK Advocates.
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American Association for Dental Research Releases Its Statement On Oral Health Care Within Health Care Reform
On July 14, the American Association for Dental Research released its policy statement titled "Oral Health Care within Health Care Reform," which focuses on the scientific base of oral health and its associations to other aspects of health.
Diagnostics

Therapy For Parkinson's, Other Diseases, Advanced By ORNL

By miniaturizing a device that monitors the delivery of healthy cells, researchers at Department of Energy"s Oak Ridge National Laboratory are developing a powerful instrument for physicians to use in treating patients with Parkinson"s syndrome, brain tumors and other diseases. While cell replacement therapies can be effective, the challenge is to deliver a sufficient quantity of healthy cells, said Boyd Evans III of the lab"s Measurement Science and Systems Engineering Division. "Regardless of the of cells and the location of delivery, there is a great need to improve cell viability after the cells are transplanted," Evans said. "The vast majority of transplanted cells do not survive more than 24 hours regardless of their ." Studies have shown that merely implanting more cells does not necessarily increase the number that survive and differentiate into dopamine-producing, or viable, cells in Parkinson"s models. The key is being able to deliver precise quantities of healthy cells to a targeted location. This requires the ability to determine if the cells are viable upon delivery and the ability to make meaningful measurements. ORNL"s proprietary instrumented cell delivery catheter allows physicians to do just that. "Our approach consists of monitoring cells that are implanted using a catheter equipped with a fiber optic probe to perform fluorescence-based cytometric measurements on cells as they exit the port at the catheter tip," Evans said. These measurements confirm that the cell is alive and provide indications of the cell"s health. "What we have done is taken the function of a laboratory instrument and put it on the tip of a catheter that can make measurements inside the brain," Evans said. Results from several studies underscore the value of delivering a highly controlled amount of tissue into the host brain, and understanding cell viability at the delivery point is critical for meaningful comparison of experimental results, according to Evans. The instrumented catheter is part of a larger effort to develop a complete system for collecting healthy tissue from an individual who is both the donor and recipient, expanding this tissue in vitro and implanting the tissue under monitored conditions. Joining Boyd in this effort are other researchers from ORNL, George Gillies of the University of Virginia, and neurosurgeon William Broaddus and neuroscientist Helen Fillmore of Virginia Commonwealth University. Funding provided through ORNL"s Laboratory Directed Research and Development program was used to develop a prototype device and demonstrate its functionality for characterizing cell flows of cell. Following completion of the LDRD funded project, NexGen Medical Systems and Kopf Family Foundation at the University of Virginia, and the Cullather, Hord and Hafner Funds at Virginia Commonwealth University worked on other issues associated with flows of slurries of cells, such as cell delivery, cell selection and culturing technique. Ron Walli DOE/Oak Ridge National Laboratory


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