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Chicago Students To Get Lessons On Diagnostic Testing From The "Unsung Heroes" Of The Clinical Lab Profession
Chicago high school students interested in science and health care will get a chance to learn about diagnostic tests and the laboratory professionals who perform them during the American Association for Clinical Chemistry"s 2009 Clinical Lab Expo on July 21 and 22.
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Carbon Monoxide Prevents Clotting
Researchers led by Drs. James F. George and Anupam Agarwal at the University of Alabama at Birmingham have found that carbon monoxide (CO) can protect against arterial clotting. They report their data in the July 2009 issue of the American Journal of Pathology.
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Nexavar® In Combination With Chemotherapy Shown To Extend Progression-Free Survival In Patients With Advanced Breast Cancer
Bayer HealthCare AG and Onyx Pharmaceuticals, Inc. announced that their first cooperative group-sponsored randomized Phase II trial in advanced metastatic breast cancer met its primary endpoint of progression-free survival. The study evaluated Nexavar® (sorafenib) tablets in combination with the oral chemotherapeutic, capecitabine, in patients with locally advanced or metastatic HER-2 negative breast cancer. Study findings demonstrated that the median progression-free survival was extended in patients treated with Nexavar and capecitabine compared to patients receiving capecitabine and placebo. These results were statistically significant (p-value = 0.0006). In this trial, the safety and tolerability of the combination was as expected and did not show any new or unexpected toxicities. A complete data analysis from this study is expected to be presented at an upcoming scientific meeting.
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Repeated Verbal Encouragement Fails To Increase Physical Activity After Stroke

Repeated encouragement and verbal instruction do not motivate stroke survivors to be physically active, and other more intensive strategies need to be found, concludes a study published on bmj.com. It is well known that even moderate physical activity can reduce the risk of cardiovascular disease and first stroke and physical exercise is also recommended for stroke survivors. Counselling on physical activity can motivate some elderly sedentary people to improve their level of physical activity, and previous studies have shown that physical activity can improve balance, walking ability and fitness in stroke patients. But little is known about which interventions to promote physical activity in stroke survivors are effective. So Professor Gudrun Boysen and her team carried out a randomised trial to examine if the low-cost intervention of repeated encouragement and verbal instructions on how to exercise could persuade stroke patients to be more physically active in the long-term. They recruited 314 stroke patients aged 40 years or older from four stroke centres in Denmark, China, Poland, and Estonia and randomised them to receive either an instructed training programme from a physiotherapist to promote physical activity prior to discharge and at six follow-up visits, or to follow-up visits with no instructions about physical activity. Levels of physical activity were measured using the Physical Activity Scale for the Elderly (PASE) including walking, light sport, housework and working. A higher score represented a higher level of activity. Findings showed that repeated encouragement and verbal instruction did not result in a measurable increase in physical activity. Mean PASE scores were 69.1 in the intervention group and 64.0 in the control group. In addition, the intervention had no significant effect on death, recurrent stroke, heart attacks, or falls or fractures. Our results show that stroke patients are: "Inclined to low levels of physical activityò€¦and more intensive strategies seem to be needed to promote physical activity after ischaemic stroke," conclude the authors. Link to paper British Medical Journal


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