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FDA Adds Strong Warnings To Anti-Smoking Drug Labels
"The Food and Drug Administration announced (Wednesday) that it is requiring the smoking-cessation drugs Chantix and Zyban to carry the strongest type of safety warning possible to alert patients that the medications can cause serious mental health problems, including depression and suicide," the Washington Post reports (Stein, 7/1).
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Senate Judiciary Committee Vote On Sotomayor Reset For July 28
The Senate Judiciary Committee on Tuesday postponed its vote on Supreme Court nominee Sonia Sotomayor until July 28 at the request of Republican members who said they need one more week to review written answers she recently submitted to the panel, CongressDaily reports. Both Republicans and Democrats expect Sotomayor to be approved by the committee and confirmed by the Senate, CongressDaily reports (CongressDaily, 7/21).The delay came as Senate Republicans continued to weigh whether they would vote to confirm Sotomayor, the Wall Street Journal reports. Sen. Susan Collins (R-Maine) announced plans to vote for Sotomayor and issued a statement calling the judge "committed to applying the law impartially without bias or favoritism." Four other moderate Republicans have said they will support Sotomayor, and Senate Judiciary Committee Chair Patrick Leahy (D-Vt.) indicated that more might follow suit. "There are a number of Republicans who have announced they plan to vote for her," Leahy said, adding, "There are a number of others who"ve not made that announcement yet, but plan to vote for her" (Peterson, Wall Street Journal, 7/21). Leahy said he is confident that Sotomayor will be confirmed in time for the Supreme Court"s first meeting on Sept. 9.Some strong conservatives, including Senate Minority Leader Mitch McConnell (Ky.), have said they will oppose Sotomayor (Hirschfeld Davis, AP/Denver Post, 7/22). Among the Senate Republicans who have not announced their intentions are Sens. John Cornyn (Texas), who serves on the Judiciary Committee, and Judd Gregg (N.H.) (Wall Street Journal, 7/21).NARAL Endorses Sotomayor NARAL ProChoice America recently said that it will endorse Sotomayor, the AP/Seattle Times reports. The group said that Sotomayor"s testimony shows that she is a stronger supporter of privacy rights than the last two Supreme Court nominees -- Chief Justice John Roberts and Justice Samuel Alito. Sotomayor said several times during her confirmation hearings that privacy rights include a woman"s right to have an abortion, NARAL said. According to the AP/Times, NARAL did not endorse Sotomayor until now because of uncertainty over her views on abortion rights (Hirschfeld Davis, AP/Seattle Times, 7/21).
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Illinois Public Health Director Presents At H1N1 Flu Preparedness Summit To Further Prepare For Possibility Of More Severe H1N1 Outbreak In The Fall
Speaking at a national summit this week on H1N1 flu preparedness, Dr. Damon T. Arnold, state public health director, stressed the need to prepare for the possibility the fall flu season could be more severe than normal.
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Recognizing 'Intoxication'

One well-known and often deadly consequence of alcohol intoxication is impaired driving. Yet still today, it is difficult for even trained observers to fully identify "intoxication," given that so many factors contribute to it. This review examines the very definition of intoxication, as well as methods designed to prevent impaired driving. The review will be published in the September issue of Alcoholism: Clinical & Experimental Research and is currently available at Early View. "It is important to understand and recognize intoxication because of the risk for injury that results from it," said John Brick, lead author and executive director of Intoxikon International. "Understanding and recognizing an intoxicated person can help us make decisions about allowing a person to drive, accepting a ride from someone, or cutting off a drinker." Key points of the review include: * "Obvious intoxication" as defined in some courts is not always the same as "visible intoxication." "While most people would use these terms interchangeably to mean that someone was clearly drunk," said Brick, "laws in some states differentiate between the terms. For example, in some states "obvious" intoxication means that if someone has consumed a large number of drinks, it should be obvious that they are intoxicated and not capable of driving. Other state laws define "visible" intoxication as specific types of behavior, such as trouble walking, slurred speech and other common signs of alcohol intoxication. Thus, it is possible to have a unique legal situation where someone is obviously intoxicated, but not visibly intoxicated based on specific legal definitions." * In most people reliable signs of intoxication are present by casual observation at a blood alcohol concentration (BAC) of 150 mg/dl or more, even in most tolerant individuals. At a BAC of less than 150 mg/dl, signs of visible intoxication are not reliably present in most drinkers, and the likelihood of identifying signs of impairment is less than chance. "This presents a particular challenge to preventionists," said Brick. "For example, how do you intervene or make an informed decision about driving with someone if they do not appear visibly intoxicated? People who are too impaired to drive are not typically staggering, slurring their speech, or presenting gross signs of intoxication." Unfortunately, there is no easy way to determine how someone can reach a BAC of 150 mg/dl, he added. "A very small woman drinking rapidly could attain a BAC of 150 mg/dl with only four standard drinks, whereas a large man might require 10 or 12 such drinks, again depending on how long they were drinking and other scientific factors," he said. "While these analyses can be calculated scientifically based on specific individuals and circumstances, for general purposes it may be better to focus on observable signs of intoxication." * Drink counting can be a useful prevention approach in some cases. In situations where exceptionally tolerant individuals do not show signs of visible intoxication even though they are very intoxicated, the only way to know if they are intoxicated might be to count drinks, Brick explained. "Although helpful in some cases, this is not without difficulty because you do not know how much the person consumed before they started drinking at your restaurant or party," said Brick. "Also, if you have a policy that allows a certain number of drinks per hour, for example, you may rely on counting rather than paying attention to behavior, and end up overserving. Drink counting is also problematic in a busy bar, restaurant, or social gathering ò€¦ and drink sizes can vary widely." He said there is a need for further research to establish a reasonable maximum number of drinks to be served, coupled with training to identify signs of intoxication. "Our review is important for scientists, law enforcement and the legal community, and particularly everyday people," said Brick. "We want readers to know that just because someone who has been drinking does not look visibly intoxicated it does not mean they are not impaired to drive. Similarly, if after drinking someone is showing one or more signs of visible intoxication such decreased inhibitions, doing or saying things they would not if sober, or psychomotor impairment, showing trouble walking, standing, or slurred speech, or cognitive impairment, as in easily confused, or impaired memory, judgment and mental tasks, then that person is probably well above the legal definition of intoxication in the US and probably has a BAC in excess of 150 mg/dl. Their risk for a serious accident is also very high." While prevention efforts have become more sensitive to drinking and driving, he said, establishing "intoxication" has also become more dependent on special tests, such as those used by police, and not available to the general public. "Ultimately," he said, "if there is uncertainty as to whether someone is intoxicated, it is better to err on the side of caution, terminate service, and arrange for alternate transportation." John Brick, Ph.D., M.A., F.A.P.A. Intoxikon International Alcoholism: Clinical & Experimental Research


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