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Teasing Apart T Helper Cells
The cytokine IL-9 promotes a multiple sclerosis-like disease in mice, according to a new study by Nowak et al. published online in the Journal of Experimental Medicine. In a related Commentary, Richard Locksley discusses the molecular and genetic regulation of cytokine production by CD4+ T helper (Th) cells and the plasticity among different Th subsets. The Commentary was published online in the Journal of Experimental Medicine on Monday, July 27th.

Blogs Comment On Tiller's Murder, Supreme Court Nomination
The following summarizes selected women"s health-related blog entries.~ "The Murder of Dr. Tiller, a Foreshadowing," Cristina Page, Birth Control Watch: Page writes, "For those who would like to think" that the "murder in church of Dr. George Tiller ... is an isolated incident, here"s the horrifying news: You are wrong." She continues, "The pattern is clear and frightening." According to Page, there were several murders of abortion providers and even more attempted murders during the administration of former President Clinton, the first president to support abortion rights. However, during the Bush administration, "not only were there no murders, there were no attempted murders," save for a single bombing of an abortion clinic, according to Page. She writes that Tiller"s murder occurred five months into the administration of President Obama, the nation"s second president who supports abortion rights. Page adds, "One can only conclude that like terrorist sleeper cells, these extremists have now been set in motion. Indeed the evidence is already there. The chatter, the threats, the hate-filled rhetoric, are abundant." According to Page, "The pro-choice movement, specifically our abortion providers, are in the greatest danger of violence when we take power." She adds, "The murder of Dr. Tiller suggests that violence against abortion providers may be far more linked to the power, or lack thereof, antiabortion groups have politically than to laws designed to increase penalties against such acts." Page continues that abortion-rights opponents "will put out carefully worded press statements condemning the murder of Dr. Tiller, as became routine for them during the Clinton years." Page concludes, "But unless the rhetoric they choose from now on becomes careful too -- they may be the enablers of murder and terror" (Page, Birth Control Watch, 5/31).~ "Where Will Women Go Now?" Kate Harding, Salon"s "Broadsheet": "If any good can come of the murder of Dr. George Tiller, ... perhaps it"s the opportunity to have a conversation about the reality of termination in the second and third trimesters," Harding writes. She adds, "Anti-choice activists often cast late-term abortions as the murder of a viable baby at the whim of a woman who doesn"t wish to be inconvenienced, carried out by a doctor who looks at her and sees only cartoon dollar signs." According to Harding, "such misinformation and outright lies about procedures that are in fact rare and only performed when medically necessary are what led anti-choice activists to call Tiller "America"s Doctor of Death" and accuse him of running a "murder mill."" The "reality" is that Tiller helped "women in absolutely desperate circumstances, when almost no one else would," Harding writes, adding, "Since the news of Dr. Tiller"s murder broke, personal narratives from people who used his services have been appearing around the Web." Harding talked to Susan Hill, president of the National Women"s Health Foundation, which referred girls and women to his clinic. Hill said, "We always sent the really tragic cases to Tiller." Harding reports that these included "women diagnosed with cancer who needed abortions to qualify for chemotherapy, women who learned late in their pregnancies that their wanted babies had fatal illnesses and rape victims so young they didn"t realize they were pregnant for months." According to Harding, "The trauma of receiving such a diagnosis is only compounded by the difficulty of obtaining a late-term abortion." Harding asked Hill "where women who need late-term abortions can go now," and says that Hill"s "response was bleak." Hill added that she doesn"t know where she will send "those really tragic cases"(Harding, "Broadsheet," Salon, 6/1). ~ "How I (and Other "Pro-Life" Leaders) Contributed to Dr. Tiller"s Murder," Frank Schaeffer, Huffington Post blogs: "My late father and I share the blame (with many others) for the murder of Dr. George Tiller," Schaeffer writes, adding, "Until I got out of the r
News of the day
New Code Of Ethics For More Transparent Medical Technology Industry
RAJ Devices, the regulatory affairs journal published by Informa and covering the medical technology industry, has published a comprehensive feature on how companies in the US can comply with a much stricter code of ethics that medical technology industry association AdvaMed will launch on 1 July.
Endocrinology

Offshore Industry Making Good Progress On Safety, But Sustained Effort Required, UK

18 months on from the landmark KP3 report, a "snapshot" review concludes that though the safety of the UK"s offshore installations is improving, the work is by no means complete and will require sustained effort and investment. The review, carried out by the Health and Safety Executive (HSE), warns that the momentum for improvement must continue through the current challenging economic climate. The original Key Programme 3 Report, published in November 2007, followed a major three-year investigation into safety on more than 100 offshore installations. Judith Hackitt, the HSE Chair said: "There are a number of positives to draw from this review, most notably that work has been undertaken to deal with all the issues that posed the most serious concern. We do recognise the serious commitment of the industry in making the improvements and the considerable res that are required. "It is also important that we thank the trade unions, industry trade associations and the workforce themselves in co-operating fully with us to enable us to take forward this review. "But this is still a "work in progress" and the momentum for improvement must continue. "The economic climate does pose a real challenge, but we have been here before. Learning from past mistakes means not squeezing key res at the very time aging installations and infrastructure need investment. "Strong leadership within offshore oil and gas companies remains imperative. Safety has to remain top of the agenda. "HSE made clear at its recent strategy launch that the recession must not become an excuse for cutting back on health and safety in any sector. Nowhere is this more true than in offshore operations where there can be no excuse for another Piper Alpha disaster." Key findings of the review include: - Remedial work has taken place to rectify matters giving serious cause for concern, such as fire doors and deluge systems. - Considerably raised awareness of the need for effective process safety management and major hazard risk controls. - Leadership in integrity management is now firmly on the industry"s agenda and has been effectively promoted through the sector. - Good progress has been made on fabric and general plant maintenance, but aging infrastructure means that this will be an ongoing challenge. - Evidence culture in the industry is changing with more open sharing taking place between organisations. - Issues regarding competence are less acute, with the industry devoting significant res to training and major hazard awareness and with major hazard risk controls and the role of installation integrity better understood by the offshore workforce. - Opportunities remain for further improving involvement by the workforce and safety representatives. Added Ian Whewell, Head of HSE"s Offshore Division: "Though the findings of this review are encouraging, the challenges are ongoing and should not be underestimated. "The offshore infrastructure continues to get older and remedial work in some areas is yet to be completed. Momentum must continue to prevent the assets degrading to the unacceptable levels identified in the 2007 KP3 report. "Though we appreciate that fluctuating demand cycles provide further challenges to the industry in planning and allocating res, this will not be permitted as an excuse for poor asset integrity. "Because of the changing nature of ownership within the UK Continental Shelf, it is also essential that maintenance histories are secured and legacy information on asset integrity passed to new operators. "The benefits of good safety are unchanged even in the current downturn. Good safety is good business and the benefits of well maintained, safe and efficient plant and equipment are not only obvious but vital to ensure the long term future of the UK offshore oil and gas industry." The KP3 review was commissioned by the Secretary of State for Work and Pensions in July 2008: Lord McKenzie, DWP Minister with responsibility for health and safety said: "I am encouraged by the review and the response of industry leaders - there is evidence of good progress in addressing the issues identified by the original KP3 Report. "The review was commissioned on the 20th Anniversary of the Piper Alpha Disaster and I hope that, for those most deeply affected by the Disaster, the review"s findings are at least a step in the right direction. "Of course there is still more to do - although there is increasing workforce awareness of major hazard risks, the review has been useful in identifying areas where improvement is required to strengthen safety culture and a continued effort is now necessary to sustain that momentum. The report findings are based on feedback from industry stakeholders, HSE Offshore Division inspection reports and case studies, work undertaken by the Workforce Involvement Group of the Offshore Industry Advisory Committee (OIAC) and a large-scale survey of the workforce. Notes 1. Judith Hackitt, Chair of the Health and Safety Executive and Ian Whewell, Head of the Offshore Division will be available for interview. A media briefing will be held at 9.30am at Lord Cullen House, HSE"s offices in Aberdeen. 2. A copy of the KP3 review is available from 14 July on the HSE website at http://www.hse.gov.uk/offshore/kp3review.pdf 3. Asset integrity can be defined as the ability of an asset to perform its required function effectively and efficiently whilst protecting health, safety and the environment. Asset integrity management is the means of ensuring that the people, systems, processes and res that deliver integrity, are in place, in use and will perform when required over the whole lifecycle of the asset. 4. Industry stakeholders who provided feedback for the review were Oil & Gas UK, Offshore Contractors Association (OCA), International Association of Drilling (IADC), International Marine Contractors (IMCA), British Rig Owners Association (BROA). Union input was via the Workforce Involvement Group. 5. The Workforce Involvement Group is a tri-partite, cross-industry work group which includes representatives from HSE, the UNITE and RMT unions, three offshore trade associations and individual workforce representatives. 6. The Offshore Workforce Survey was commissioned by HSE to carry out a quantitative survey among the 26,500 offshore workers based on installations in the North Sea. One of the key objectives was to assess the views of both direct employees of oil and gas companies and contractors to gain an insight into how healthy and safety is managed, especially as far as asset integrity and major hazard potential is concerned, and what role the workforce plays in health and safety management. This report can be viewed at http://news.hse.gov.uk/2009/06/19/offshore-workforce-survey-report 7. The original Key Programme 3 Investigation (report published November 2007) was prompted by offshore installation integrity failures which were responsible for significant hydrocarbon releases and two deaths in 2002. These reinforced concerns that the risk of major accidents on the UK continental shelf appeared to be rising, making asset integrity inspections a priority for HSE. The original report can be viewed at http://www.hse.gov.uk/offshore/kp3.pdf Health and Safety Executive


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