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UK Tops The List Of 213 Countries At Extreme Risk To The Spread Of Swine Flu
A Warwick Business School professor and one of the founders of global risks specialist, Maplecroft, has released three new maps and indices revealing the countries most at risk from an influenza pandemic.

Appetite Increased By Action Of Ghrelin Hormone Leading To Accumulation Of Abdominal Fat
The ghrelin hormone not only stimulates the brain giving rise to an increase in appetite, but also favours the accumulation of lipids in visceral fatty tissue, located in the abdominal zone and considered to be the most harmful. This is the conclusion of research undertaken at Metabolic Research Laboratory of the University Hospital of Navarra, published recently in the International Journal of Obesity.
News of the day
Exelixis Reports Encouraging Phase 1 Data To Be Presented At ASCO For XL228, A Multi-Targeted Inhibitor Of Key Cancer Signaling Kinases
Exelixis, Inc. (Nasdaq: EXEL) today reported encouraging data from an ongoing Phase 1 dose-escalation trial of XL228 in patients with advanced malignancies. XL228 is a small molecule inhibitor of insulin-like growth factor type 1 receptor (IGF1R), SRC, Aurora kinases, and fibroblast growth factor receptor types 1, 2, and 3 (FGFR1-3), which are associated with cancer cell proliferation, survival, and metastasis. The compound also inhibits BCR-ABL, including the T315I mutant form which is resistant to currently approved inhibitors. David Smith, MD, Professor of Medicine at the University of Michigan, an investigator on the Phase 1 trial, will present the data in an oral session (Abstract #3512) beginning at 4:15 p.m. local time on Saturday, May 30, 2009, at the American Society of Clinical Oncology Annual Meeting, which is being held May 29-June 2 in Orlando.
Public Health

Hospitalization Of The Poor Much Higher For Asthma, Diabetes And Other Potentially Preventable Diseases

Hospital admissions of Americans from the poorest communities for asthma and diabetes were 87 percent and 77 percent higher, respectively, than admissions for patients from wealthier areas for the same diseases, according to the latest News and Numbers from the Agency for Healthcare Research and Quality. Asthma and diabetes are potentially preventable conditions because good outpatient care can help to prevent the need for hospitalization. Despite national efforts to eliminate health care disparities, low-income Americans continue to have higher hospital admission rates for asthma and many other conditions. AHRQ"s analysis found that compared to Americans from wealthier areas: - Patients from the poorest communities were more likely to be hospitalized for chronic obstructive pulmonary disease, 69 percent; congestive heart failure, 51 percent; skin infections, 49 percent; and dehydration, 38 percent. - In addition, patients from the poorest communities were more likely to be admitted for severe blood infection, stroke, and depression. - Furthermore, hospitalized Americans from the poorest communities were 80 percent more likely to receive hemodialysis for kidney failure, and they were more likely to undergo procedures often done on an outpatient basis, such as eye and ear procedures (81 percent more likely). Infants from poor areas were 47 percent more likely to be vaccinated for hepatitis B. This AHRQ News and Numbers is based on data in Hospital Stays among People Living in the Poorest Communities, 2006. The report uses statistics from the 2006 Nationwide Inpatient Sample, a database of hospital inpatient stays that is nationally representative of inpatient stays in all short-term, non-Federal hospitals. The data are drawn from hospitals that comprise 90 percent of all discharges in the United States and include all patients, regardless of insurance type, as well as the uninsured. AHRQ


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